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Hōʻike huahana

1. Huahana Huahana

Nā mea hana nui:

Paeoniflorin (ʻoi aku ma mua o 40%): He mea anti-koʻo a me ka neuroprotective

Huina Monoterpene Glycosides ( ʻOi aku ma mua a i ʻole like me 80%): Loaʻa ka oxypaeoniflorin, benzoylpaeoniflorin

Polyphenols: ʻakika Gallic, ʻakika ellagic (antioxidant)

Polysaccharides (5-10%): Ka hana immunomodulatory

Puna Hua: Nā aʻa maloʻo o Paeonia lactiflora Pall. (Ranunculaceae)

Na Waiwai Kino: Keʻokeʻo a hiki i ka pauka ʻeleʻele, ʻawaʻawa iki, hiki ke hoʻoheheʻe ʻia i ka wai

Nā kikoʻī:

Nā metala kaumaha (Pb, Cd, As)<5ppm

Kūlike nā koena pesticide me CP2020

Ka helu HPLC o paeoniflorin (RSD<2%)

2.Product Profile

Loaʻa ka unuhi maʻamau ma o ka unuhi -maha haʻahaʻa dynamic countercurrent, e hōʻike ana:

ʻEkolu mau hana kumu:

ʻAi -Ahu a me Analgesic:

Kāohi COX-2 (IC50=3.2μM)

Hoʻemi i nā pae TNF- /IL-6 (ma ke kino ↓35%)

Neuroprotection:

Hoʻoulu i ke ala BDNF (hoʻomaikaʻi i ka hopohopo / kaumaha)

Hoʻemi -amyloid deposition (kūpono i nā kumu hoʻohālike o Alzheimer)

Hoʻoponopono Gynecological:

Hoʻopau i ka dysmenorrhea mua (50%↓ nā helu VAS)

Hoʻololi i nā mea loaʻa estrogen (ER- / kaulike)

Nā pōmaikaʻi me nā NSAID:
✓ ʻAʻohe GI irritation (COX-1 sparing)
✓ ʻElua -ʻaoʻao hoʻololi kino (koe Th1/Th2)
✓ Monographed ma Chinese Pharmacopoeia (CP) a me Japanese Pharmacopoeia (JP)

ʻIkepili ʻenehana

Kaʻina hana	Nā Hana Hou	Nā Kūlana QC
Haʻahaʻa -weli kūʻē i ka wela	Pale i nā pūhui thermolabile (<45°C)	UPLC-QTOF piha-palapala manamana lima
Molecular imprinting hoʻomaʻemaʻe	Paeoniflorin purity >95%	ʻIke UV (λ=230nm)
ʻO ka ua haʻihaʻi polysaccharide	Hoʻonui i ka 10-50kDa i nā hakina hana	Phenol-sufuric acid assay
E pāpaʻi -microencapsulation maloʻo	Hoʻemi i ka hygroscopicity (moisture<5%)	36-mahina ho'āʻo kūpaʻa wikiwiki

Nā Pōmaikaʻi hoʻokūkū

Hōʻike -Ma muli o:

Hoʻopaʻa ʻia ma ka WHO Traditional Medicine Registry (no ka dysmenorrhea/inflammation)

32 RCTs (me ka Phase II fibromyalgia ho'āʻo)

Palapala Palekana:

LD50 >15g/kg (ke ʻawaʻawa o ka ʻiole)

ʻAʻohe hopena ʻaoʻao estrogenic (kūpono no ka -hoʻohana lōʻihi)

Paʻa:

24-mahina mālama ola (aluminum laminate packaging)

Gastric acid-resistant (>90% paʻa ma pH2 no 2h)

Nā noi

① Nā lāʻau lapaʻau

ʻAha mau: ʻO nā papa i uhi ʻia -enteric (500mg me 200mg paeoniflorin)

Nā maʻi neurodegenerative: Nā kiʻiʻoniʻoni sublingual (me huperzine A)

② Ola o na Wahine

Hoʻomaha ʻo Dysmenorrhea: ʻO nā ʻāpana wela (i hui pū ʻia me ka ʻaila Angelica)

Kākoʻo menopausal: Nā pāpili Phytoestrogen (me ka cohosh ʻeleʻele)

③ Nā meaʻai kūpono

Kākoʻo naʻau: GABA-mea inu i hui ʻia

Mālama hui: Type II collagen pauda huila

④ Nā mea hoʻonaninani

Nā serum -ʻulaʻula kūʻē: Lapaʻau Rosacea (0.5% ka hoʻopaʻa ʻana)

Kū'ē -glycation: Wrinkle essences ('ākeʻe i ka hoʻokumu ʻana o AGEs)

⑤ Ola holoholona

ʻO ka hoʻomaha ʻana i nā holoholona: Nahu ka hopohopo ʻīlio

Aquaculture: Mea hoʻohui -stress no ka iʻa mahiʻai

Mākeʻakaʻike

E hōʻea ka mākeke anti-inflammatory - honua botanical a hiki i $8.7B ma ka makahiki 2025. Nā hana i manaʻo ʻia:

Hoʻouna ʻia:

Nā nanoparticles i hoʻopaʻa ʻia i ka lolo (BBB komo)

Hoʻokuʻu kikoʻī -kona (no IBD)

Nā Hana Hana Hana:

Hoʻohui pū ʻia (probiotic ka hoʻololi ʻana i ka ʻōpū-lolo-uterus axis modulation)

Hoʻohui Mea Lapaʻau:

Nā ʻāpana microneedle hiki ke hoʻoheheʻe ʻia (transdermal delivery)

Pono e hoʻopaʻa inoa: "E akahele i ka wā o ka hāpai ʻana" (contraindication kuʻuna)

Loaʻa nā koho: Paeoniflorin māka (40%/60%/90%)

Hoʻokō:

ʻO ka Pharmacopoeia Kina 2020

Kuhikuhi Hua Laau Laau Laau Kuuna EU

No nā COA i hana ʻia a i ʻole ka hōʻoia ʻana, e kelepona i kā mākou hui ʻenehana.

Hoʻopaʻa a mālama

Hoʻopili: 1kg / ʻeke pepa, 25kg / pahu fiber (hiki ke hoʻololi ʻia)
Ka mālama ʻana: E kūʻai ma kahi maloʻo, hoʻopaʻa ʻia a pale ʻia mai ka mālamalama
Ola Ola: 24 mahina (ma lalo o nā kūlana i wehe ʻole ʻia)

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